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WebMD discusses dangerous things you should never do when trying to lose weight. The allure of a drug promising weight loss without dieting means that sadly, history is repeating itself. Topics. Drugs The H word Human biology Medical research. Great flavor Meets Great Nutrition. No fillers and always Gluten/Soy Free!. May 12, · Just curious, anyone else ever notice any weight loss from taking Ayahuasca or smoking Changa/vaping DMT? In Ayahuasca's case, i don't think it has.